Neoadjuvant therapy is administered therapeutic agents prior to primary treatment. One example is neoadjuvant hormone therapy before radical radiotherapy for prostate adenocarcinoma. Neoadjuvant therapy aims to reduce the size or level of cancer before using radical treatment interventions, thereby making the procedure easier and more likely to succeed, and reducing the consequences of wider treatment techniques that will be needed if the tumor is not reduced. size or level.
Another related concept is that neoadjuvant therapy works in micrometastasis. Downstaging is then a surrogate marker of the efficacy of undetectable dissemination, which results in longer survival compared with surgical strategies alone.
This systemic therapy (chemotherapy, immunotherapy or hormone therapy) or radiation therapy is commonly used in locally developed cancers - where doctors plan surgery at a later stage. The use of such therapy can effectively reduce the widespread difficulty and morbidity of the procedure.
Source of the article : Wikipedia
0 Comments